Box 1: 3 -
If you have data sources in multiple regions, create a Recovery Services vault for each region.
The File Shares and VMs are located in three Regions: West US, East US, Central US.
Box 2: 6 -
A backup policy is scoped to a vault. For each vault we need one backup policy for File Shares and one backup policy for VM.
Note:
Back up the Azure file shares and virtual machines by using Azure Backup
Reference:
https://docs.microsoft.com/en-us/azure/backup/backup-create-rs-vault
https://docs.microsoft.com/en-us/azure/backup/guidance-best-practices